Quick answer
🟡 Yes, but tightly. A nurse in Knoxville earns roughly $74,258/yr (~$4,601/mo take-home) and a 1BR costs $1,200/mo — that's 26% of take-home on rent. The standard is 30% or less.
TN · 2026
Can a Registered Nurse Afford to Live in Knoxville?
Using local salary estimates and Knoxville's actual cost of living — rent, taxes, utilities, and groceries — here's the real monthly picture for a nurse in Knoxville, TN in 2026.
Monthly Budget Breakdown
Gross monthly salary
$74,258/yr local estimate
$6,188
Taxes (federal + state + FICA)
None state income tax
-$1,587
Monthly take-home
After all taxes
$4,601
1BR rent
26% of take-home
-$1,200
Utilities
Electric, gas, internet avg
-$150
Groceries
Single-person estimate
-$365
Transport
Car or transit average
-$350
Left for everything else
Dining, clothing, fun, savings
$2,536
At a 40% savings rate on discretionary income, a nurse in Knoxville could save roughly $12,168/year after covering all essentials.
What Does 26% Rent Burden Mean?
The standard rule of thumb is to spend no more than 30% of gross income on rent. At 26% of take-home pay, a nurse in Knoxville is near the limit. Livable, but there's little buffer for emergencies or lifestyle upgrades.
No state income tax in TN meaningfully helps. A nurse earning $74,258/yr saves roughly $3,342/year compared to a 4.5% state income tax state — that's equivalent to one month of rent.
These numbers use a local salary estimate of $74,258/yr — adjusted from the national Registered Nurse median of $81,220/yr based on Knoxville's cost of living index. Actual salaries vary by employer, experience, and specialization.
Best Neighborhoods in Knoxville for a Registered Nurse
Based on walkability, rent levels, and quality of life — not just lowest price.
Downtown
Historic buildings, Market Square (farmers market, restaurants), walkable loft living. 1BR $1,250-$1,500; 2BR $1,500-$1,800.
Old North Knoxville
Gentrifying Victorian homes, locally-owned cafes, young professional vibe. 1BR $1,150-$1,350; 2BR $1,400-$1,650.
Bearden
Upscale suburban, newer homes, shopping, close to UT. 1BR $1,100-$1,300; 2BR $1,350-$1,600.
Frequently Asked Questions
What is the average salary for a Registered Nurse in Knoxville?
A Registered Nurse in Knoxville earns approximately $74,258 per year, based on the national BLS median of $81,220/yr adjusted for Knoxville's cost of living. Actual pay varies by employer, experience, and specialization.
Is Knoxville affordable for a nurse in 2026?
Manageable. Rent takes 26% of take-home, which is right at the limit. A nurse can make it work but should keep other expenses lean.
How much take-home pay does a Registered Nurse get in Knoxville?
After federal taxes, no state income tax, and FICA, a Registered Nurse earning $74,258/yr takes home roughly $4,601/month in Knoxville.
What is the rent-to-income ratio for a Registered Nurse in Knoxville?
A 1-bedroom apartment in Knoxville costs a median of $1,200/month. On a Registered Nurse salary, that's 26% of monthly take-home pay. Financial experts recommend keeping this below 30%.