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Quick answer

Yes — comfortably. A physician assistant in Louisville earns roughly $108,729/yr (~$5,967/mo take-home) and a 1BR costs $1,080/mo — that's 18% of take-home on rent. The standard is 30% or less.

KY · 2026

Can a Physician Assistant Afford to Live in Louisville?

Using local salary estimates and Louisville's actual cost of living — rent, taxes, utilities, and groceries — here's the real monthly picture for a physician assistant in Louisville, KY in 2026.

Comfortable18% rent burden

Monthly Budget Breakdown

Gross monthly salary

$108,729/yr local estimate

$9,061

Taxes (federal + state + FICA)

4.5% state income tax

-$3,094

Monthly take-home

After all taxes

$5,967

1BR rent

18% of take-home

-$1,080

Utilities

Electric, gas, internet avg

-$140

Groceries

Single-person estimate

-$335

Transport

Car or transit average

-$350

Left for everything else

Dining, clothing, fun, savings

$4,062

At a 40% savings rate on discretionary income, a physician assistant in Louisville could save roughly $19,500/year after covering all essentials.

What Does 18% Rent Burden Mean?

The standard rule of thumb is to spend no more than 30% of gross income on rent. At 18% of take-home pay, a physician assistant in Louisville is well within a healthy range — leaving solid room for savings and discretionary spending.

These numbers use a local salary estimate of $108,729/yr — adjusted from the national Physician Assistant median of $126,010/yr based on Louisville's cost of living index. Actual salaries vary by employer, experience, and specialization.

Best Neighborhoods in Louisville for a Physician Assistant

Based on walkability, rent levels, and quality of life — not just lowest price.

NuLu (East Market District)

Best restaurant corridor, galleries, bourbon bars, converted warehouses; 1BR $1,200–1,600

The Highlands (Bardstown Rd)

Dense bar and restaurant strip, eclectic shops, most active nightlife; 1BR $1,100–1,500

Crescent Hill

Bungalows, independent shops, walkable village, young families; 1BR $1,000–1,400

Frequently Asked Questions

What is the average salary for a Physician Assistant in Louisville?

A Physician Assistant in Louisville earns approximately $108,729 per year, based on the national BLS median of $126,010/yr adjusted for Louisville's cost of living. Actual pay varies by employer, experience, and specialization.

Is Louisville affordable for a physician assistant in 2026?

Yes. Rent takes around 18% of take-home pay — below the 30% guideline. A physician assistant can live comfortably in Louisville with room to save.

How much take-home pay does a Physician Assistant get in Louisville?

After federal taxes, 4.5% state income tax, and FICA, a Physician Assistant earning $108,729/yr takes home roughly $5,967/month in Louisville.

What is the rent-to-income ratio for a Physician Assistant in Louisville?

A 1-bedroom apartment in Louisville costs a median of $1,080/month. On a Physician Assistant salary, that's 18% of monthly take-home pay. Financial experts recommend keeping this below 30%.